"Osteoporosis" is a systemic disease Systemic: A condition due to an increase in the secretion of the parathyroids, causing elevated serum calcium, decreased serum phosphorus, and increased excretion of both calcium and phosphorus, calcium stones and sometimes generalized osteitis fibrosa cystica.of low bone mass and deterioration of bone tissue; this leads to fragility and risk of fracture.

"Osteopenia" is a decrease in bone mass which is below normal but not as severe as "osteoporosis".

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